Comparison of topological properties of functional brain networks with graph theory in temporal lobe epilepsy with different duration of disease.

ABSTRACT:

Background

Our study was performed to measure the alterations in topological properties of the functional brain network of temporal lobe epilepsy (TLE) at different durations, exploring the potential progression and neuropathophysiological mechanisms of TLE.

Methods

Fifty-eight subjects, including 17 TLE patients with a disease duration of ≤5 years (TLE-SD), 20 TLE patients with a disease duration of >5 years (TLE-LD), and 21 healthy controls firstly underwent the Attention Network Test (ANT) to assess the alertness function and received the resting-state functional magnetic resonance imaging (rs-fMRI). Next, a functional brain network was set up, and then the related graph of theoretical network analysis was conducted. Finally, the correlation between network property and t

SUBMITTER: Liang X 

PROVIDER: S-EPMC7729351 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature