Non-vitamin K oral anticoagulant use after cardiac surgery is rapidly increasing.

ABSTRACT:

Objective

The prevalence of non-vitamin K oral anticoagulant use after cardiac surgery is unknown, particularly in patients with bioprosthetic valves. We sought to define the contemporary use and short-term safety of non-vitamin K oral anticoagulants after cardiac surgery.

Methods

All patients undergoing bioprosthetic aortic valve replacement, bioprosthetic mitral valve replacement, or isolated coronary artery bypass grafting (2011-2018) were evaluated from a multicenter, regional Society of Thoracic Surgeons database. Patients were stratified by anticoagulant type (non-vitamin K oral anticoagulant vs vitamin K antagonist) and era (early [2011-2014] vs contemporary [2015-2018]).

Results

Of 34,188 patients, 18% (6063) were discharged on anticoagulation, of whom 23% wer

SUBMITTER: Beller JP 

PROVIDER: S-EPMC7729876 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature