Molecular characterization and serodiagnostic potential of two serpin proteins in Psoroptes ovis var. cuniculi.

ABSTRACT:

Background

Psoroptes ovis var. cuniculi is a common ectoparasite of wild and domestic rabbits worldwide that causes economically devastating losses in commercial rabbit husbandry and significantly affects the overall health of rabbits. Serine proteinase inhibitor (serpin) is present in almost all organisms that are involved in host-pathogen interactions, inflammatory responses, and reproductive development, among others. However, very little research has been carried out on P. ovis var. cuniculi serpins.

Methods

Two serpin genes of P. ovis var. cuniculi (Pso c 27 and PsoSP2 cDNAs) were cloned and molecularly characterized. The transcriptional profiles and tissue localization of these two serpins in P. ovis var. cuniculi were investigated by quantitative real-time PCR and imm

SUBMITTER: Gu X 

PROVIDER: S-EPMC7731772 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature