EEG Microstate Differences in Medicated vs. Medication-Naive First-Episode Psychosis Patients.

ABSTRACT: There has been considerable interest in the role of synchronous brain activity abnormalities in the pathophysiology of psychotic disorders and their relevance for treatment; one index of such activity are EEG resting-state microstates. These reflect electric field configurations of the brain that persist over 60-120 ms time periods. A set of quasi-stable microstates classes A, B, C, and D have been repeatedly identified across healthy participants. Changes in microstate parameters coverage, duration and occurrence have been found in medication-naïve as well as medicated patients with psychotic disorders compared to healthy controls. However, to date, only two studies have directly compared antipsychotic medication effects on EEG microstates either pre- vs. post-treatment or between medicat

SUBMITTER: Mackintosh AJ 

PROVIDER: S-EPMC7732503 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature