Risks of solid cancers in elderly persons with osteoarthritis or ankylosing spondylitis.

ABSTRACT:

Objectives

Patients with osteoarthritis and ankylosing spondylitis have lower cancer-related mortality than the general population. We examined risks of solid cancers at 16 sites in elderly patients with knee or hip osteoarthritis (KHOA) or ankylosing spondylitis.

Methods

In this population-based retrospective cohort study, we used US Medicare data from 1999 to 2010 to identify cohorts of persons with KHOA or ankylosing spondylitis, and a general population group without either condition, who were followed through 2015. We compared cancer incidence among groups, adjusted for age, sex, race, socioeconomic characteristics, geographic region, smoking and comorbidities.

Results

We studied 2 701 782 beneficiaries with KHOA, 13 044 beneficiaries with ankylosing spondylitis,

SUBMITTER: Ward MM 

PROVIDER: S-EPMC7733716 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature