Cardiovascular findings in classic homocystinuria.

ABSTRACT:

Objective

describe cardiovascular findings from echocardiograms and electrocardiograms in patients with Classic Homocystinuria.

Methods

this retrospective exploratory study evaluated fourteen subjects with Classic Homocystinuria (median age = 27.3 years; male n = 8, B6-non-responsive n = 9 patients), recruited by convenience sampling from patients seen Hospital de Clínicas de Porto Alegre (Brazil), between January 1997 and July 2020. Data on clinical findings, echocardiogram and electrocardiogram were retrieved from medical records.

Results

Eight patients presented some abnormalities on echocardiogram (n = 6) or electrocardiogram (n = 5). The most frequent finding was mild tricuspid regurgitation (n = 3), followed by mitral valve pro

SUBMITTER: Kalil MAB 

PROVIDER: S-EPMC7734301 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature