Convalescent plasma for pediatric patients with SARS-CoV-2-associated acute respiratory distress syndrome.
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ABSTRACT:
SUBMITTER: Diorio C
PROVIDER: S-EPMC7734626 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
Convalescent plasma for pediatric patients with SARS-CoV-2-associated acute respiratory distress syndrome.
Diorio Caroline C Anderson Elizabeth M EM McNerney Kevin O KO Goodwin Eileen C EC Chase Julie C JC Bolton Marcus J MJ Arevalo Claudia P CP Weirick Madison E ME Gouma Sigrid S Vella Laura A LA Henrickson Sarah E SE Chiotos Kathleen K Fitzgerald Julie C JC Kilbaugh Todd J TJ John Audrey R Odom ARO Blatz Allison M AM Lambert Michele P MP Sullivan Kathleen E KE Tartaglione Margaret R MR Zambrano Danielle D Martin Meghan M Lee Jessica H JH Young Pampee P Friedman David D Sesok-Pizzini Deborah A DA Hensley Scott E SE Behrens Edward M EM Bassiri Hamid H Teachey David T DT
Pediatric blood & cancer 20200904 11
There are no proven safe and effective therapies for children who develop life-threatening complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Convalescent plasma (CP) has demonstrated potential benefit in adults with SARS-CoV-2, but has theoretical risks.We present the first report of CP in children with life-threatening coronavirus disease 2019 (COVID-19), providing data on four pediatric patients with acute respiratory distress syndrome. We measured donor antibody l ...[more]
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Project description: Not available
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Project description:Circulating miRNAs in patients who underwent ARDS and needed mechanical ventilation were analyzed by next generation sequencing (NGS) in comparison with patients who had COVID-19 poor symptoms but without intensive care unit requirement.
2022-04-12 | GSE182183 | GEO