Human breast milk as source of sphingolipids for newborns: comparison with infant formulas and commercial cow's milk.

ABSTRACT:

Background

In the past two decades, sphingolipids have become increasingly appreciated as bioactive molecules playing important roles in a wide array of pathophysiology mechanisms. Despite advances in the field, sphingolipids as nutrients remain little explored. Today the research is starting to move towards the study of the sphingomyelin content in human breast milk, recommended for feeding infants.

Methods

In the present study, we performed a lipidomic analysis in human breast milk in relation with maternal diet during pregnancy, in infant formulas, and in commercial whole and semi-skimmed milks for adults. Mediterranean, carnivorous and vegetarian diets were considered.

Results

The results showed that total sphingomyelin, ceramide and dihydroceramide species are in

SUBMITTER: Dei Cas M 

PROVIDER: S-EPMC7734711 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature