Evaluating association of vaccine response to low serum zinc and vitamin D levels in children of a birth cohort study in Dhaka.

ABSTRACT:

Background

Vaccine-preventable infectious diseases are often responsible for childhood morbidity and high rates of mortality. Immune response to the vaccine is associated with multiple factors in early childhood and measured by antibody titers. Among them, micronutrient deficiencies such as vitamin D and zinc deficiencies are the most important in resource-limited settings like Bangladesh.

Objective

We aimed to evaluate the association of vaccine response to low serum zinc and vitamin D levels in children.

Methods

We evaluated vaccine response for measles and poliovirus, tetanus and pertussis toxoid, and Ig A antibody levels to rotavirus by ELISA and serum vitamin D and zinc at 7 and 15 months in the MAL-ED birth cohort of the Bangladesh site. By using population-spec

SUBMITTER: Das R 

PROVIDER: S-EPMC7735373 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature