Complement C1q as a Potential Biomarker for Obesity and Metabolic Syndrome in Chinese Adolescents.

ABSTRACT:

Background

Complement C1q (C1q) has been confirmed to be related to obesity, metabolic syndrome (MetS), and its components. However, human data regarding the associations are relatively scarce. This study aimed to investigate associations of C1q with obesity as well as MetS in Chinese adolescents.

Methods

A total of 1,191 Chinese adolescents aged 13-18 years were enrolled in this study. The biochemical and anthropometric variables of all the subjects were evaluated using standardized procedures. C1q was measured using the immunoturbidometric assay. The relationship between C1q and obesity or MetS was analyzed using multiple regression analyses.

Results

Obesity was more prevalent among participants in the highest tertile than in the lowest tertile of C1q levels. The hi

SUBMITTER: Yang X 

PROVIDER: S-EPMC7735390 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature