Long-Term Disease Burden and Survivorship Issues After Surgery and Radiotherapy of Intracranial Meningioma Patients.

ABSTRACT:

Background

Many intracranial meningioma patients have an impaired health-related quality of life (HRQoL) and neurocognitive functioning up to 4 yr after intervention.

Objective

To assess the long-term (≥5 yr) disease burden of meningioma patients.

Methods

In this multicenter cross-sectional study, patients ≥5 yr after intervention (including active magnetic resonance imaging (MRI) surveillance) were included and assessed for HRQoL (Short-Form Health Survey 36), neurocognitive functioning (neuropsychological assessment), anxiety and depression (Hospital Anxiety and Depression Scale), and work productivity (Short Form-Health and Labour Questionnaire). Multivariable and propensity score regression analyses were used to compare patients and controls, and different treatme

SUBMITTER: Zamanipoor Najafabadi AH 

PROVIDER: S-EPMC7735868 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature