Salivary measurement and mindfulness-based modulation of prescription opioid cue-reactivity.

ABSTRACT:

Background

Chronic pain patients on long-term opioid therapy (LTOT) may be at elevated risk for developing conditioned opioid cue-reactivity as their prescribed dosing schedules simultaneously function as fixed reinforcement schedules. Since opioids are typically consumed orally during LTOT, it stands to reason that opioid cue exposure might elicit conditioned salivary responses. However, no study has examined salivary cue-reactivity among opioid users during in-vivo exposure to their own prescription opioid medication.

Methods

Two samples (N = 68, N = 39) of chronic pain patients on LTOT were recruited from primary care and specialty care clinics. Study 1 aimed to determine whether chronic pain patients receiving LTOT exhibited salivary cue-reactivity to their prescribed op

SUBMITTER: Hanley AW 

PROVIDER: S-EPMC7736195 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature