Association of Direct-Acting Antiviral Treatment With Mortality Among Medicare Beneficiaries With Hepatitis C.

ABSTRACT:

Importance

Direct-acting antiviral (DAA) drugs are highly effective in curing hepatitis C virus (HCV) infection. Previous simulations showed extended life as a key health advantage of DAA drugs, but real-world evidence on the association between DAA treatment and reduced mortality is limited.

Objectives

To examine the association of DAA treatment with mortality among Medicare beneficiaries with hepatitis C.

Design, setting, and participants

This cohort study used Medicare claims data of beneficiaries who sought hepatitis C care for the first time between January 1, 2014, and December 31, 2016, after at least a 1-year washout period. Medicare Part D files were used in identifying DAA therapy initiation and completion. Death dates, demographic data, and indicators of he

SUBMITTER: Kalidindi Y 

PROVIDER: S-EPMC7737657 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature