Parental occupational organic dust exposure and selected childhood cancers in Denmark 1968-2016.

ABSTRACT:

Background

Parental occupational exposures are suggested as contributing causes of childhood cancer.

Methods

Children age< = 19, born in Denmark and diagnosed with leukemia, central nervous system (CNS) cancers and likely prenatally initiated cancers [hepatoblastoma, medulloblastoma, Wilms tumor (nephroblastoma), neuroblastoma, retinoblastoma and acute lymphoid leukemia] n = 4268 were identified using Danish registries. We randomly selected twenty-five controls per case matched on birth year and sex. Parents and their employment histories were extracted from nationwide registries. We examined occupational dust exposures perinatally and postnatally in both parents. Odds ratios (ORs) and 95 % confidence intervals (95 % CI) were estimated using conditional logistic regression.<

SUBMITTER: Volk J 

PROVIDER: S-EPMC7737883 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature