Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland.

ABSTRACT:

Background

Very few studies have explored the patterns of cardiovascular health (CVH) metrics in midlife and late life in relation to risk of dementia. We examined the associations of composite CVH metrics from midlife to late life with risk of incident dementia.

Methods and findings

This cohort study included 1,449 participants from the Finnish Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) study, who were followed from midlife (baseline from1972 to 1987; mean age 50.4 years; 62.1% female) to late life (1998), and then 744 dementia-free survivors were followed further into late life (2005 to 2008). We defined and scored global CVH metrics based on 6 of the 7 components (i.e., smoking, physical activity, and body mass index [BMI] as behavioral CVH metrics; fasting

SUBMITTER: Liang Y 

PROVIDER: S-EPMC7737898 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature