Coagulation profile of COVID-19 patients admitted to the ICU: An exploratory study.

ABSTRACT:

Background

Coagulation abnormalities in COVID-19 patients have not been addressed in depth.

Objective

To perform a longitudinal evaluation of coagulation profile of patients admitted to the ICU with COVID-19.

Methods

Conventional coagulation tests, rotational thromboelastometry (ROTEM), platelet function, fibrinolysis, antithrombin, protein C and S were measured at days 0, 1, 3, 7 and 14. Based on median total maximum SOFA score, patients were divided in two groups: SOFA ≤ 10 and SOFA > 10.

Results

Thirty patients were studied. Some conventional coagulation tests, as aPTT, PT and INR remained unchanged during the study period, while alterations on others coagulation laboratory tests were detected. Fibrinogen levels were increased in both groups. ROTEM maximum c

SUBMITTER: Correa TD 

PROVIDER: S-EPMC7737963 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature