Brain Reserve in a Case of Cognitive Resilience to Severe Leukoaraiosis.

ABSTRACT:

Objective

Leukoaraiosis, or white matter rarefaction, is a common imaging finding in aging and is presumed to reflect vascular disease. When severe in presentation, potential congenital or acquired etiologies are investigated, prompting referral for neuropsychological evaluation in addition to neuroimaging. T2-weighted imaging is the most common magnetic resonance imaging (MRI) approach to identifying white matter disease. However, more advanced diffusion MRI techniques may provide additional insight into mechanisms that influence the abnormal T2 signal, especially when clinical presentations are discrepant with imaging findings.

Method

We present a case of a 74-year-old woman with severe leukoaraoisis. She was examined by a neurologist, neuropsychologist, and rheumatologist

SUBMITTER: Szeles DM 

PROVIDER: S-EPMC7738360 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature