Association of Sedentary Time and Incident Heart Failure Hospitalization in Postmenopausal Women.

ABSTRACT:

Background

The 2018 US Physical Activity Guidelines recommend reducing sedentary behavior (SB) for cardiovascular health. SB's role in heart failure (HF) is unclear.

Methods

We studied 80 982 women in the Women's Health Initiative Observational Study, aged 50 to 79 years, who were without known HF and reported ability to walk ≥1 block unassisted at baseline. Mean follow-up was 9 years for physician-adjudicated incident HF hospitalization (1402 cases). SB was assessed repeatedly by questionnaire. Time-varying total SB was categorized according to awake time spent sitting or lying down (≤6.5, 6.6-9.5, >9.5 h/d); sitting time (≤4.5, 4.6-8.5, >8.5 h/d) was also evaluated. Hazard ratios and 95% CI were estimated using Cox regression.

Results

Controlling for age, race/ethni

SUBMITTER: LaMonte MJ 

PROVIDER: S-EPMC7738397 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature