Data preprocessing workflow for exhaled breath analysis by GC/MS using open sources.

ABSTRACT: The noninvasive diagnosis and monitoring of high prevalence diseases such as cardiovascular diseases, cancers and chronic respiratory diseases are currently priority objectives in the area of health. In this regard, the analysis of volatile organic compounds (VOCs) has been identified as a potential noninvasive tool for the diagnosis and surveillance of several diseases. Despite the advantages of this strategy, it is not yet a routine clinical tool. The lack of reproducible protocols for each step of the biomarker discovery phase is an obstacle of the current state. Specifically, this issue is present at the data preprocessing step. Thus, an open source workflow for preprocessing the data obtained by the analysis of exhaled breath samples using gas chromatography coupled with single quadru

SUBMITTER: Sola Martinez RA 

PROVIDER: S-EPMC7738550 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature