<i>Vibrio cholerae</i> O1 transmission in Bangladesh: insights from a nationally representative serosurvey.

ABSTRACT:

Background

Pandemic Vibrio cholerae from cholera-endemic countries around the Bay of Bengal regularly seed epidemics globally. Without reducing cholera in these countries, including Bangladesh, global cholera control might never be achieved. Little is known about the geographical distribution and magnitude of V cholerae O1 transmission nationally. We aimed to describe infection risk across Bangladesh, making use of advances in cholera seroepidemiology, therefore overcoming many of the limitations of current clinic-based surveillance.

Methods

We tested serum samples from a nationally representative serosurvey in Bangladesh with eight V cholerae-specific assays. Using these data with a machine-learning model previously validated within a cohort of confirme

SUBMITTER: Azman AS 

PROVIDER: S-EPMC7738617 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature