An Individual Patient Data Meta-Analysis with Colombian Studies on the Effect of Dark Chocolate Consumption on Cardiovascular Risk Parameters.

ABSTRACT:

Background

It is postulated that cocoa solids possess cardioprotective capacity by various mechanisms. In the different cocoa studies evaluating cardiovascular disease, there are no conclusive data on the role it plays in controlling the lipid profile and anthropometric variables, perhaps because the concentration of cocoa, the geographical origin of the population, and the different concentrations supplied lead to a high heterogeneity of results. This study aims to estimate the effect of consuming cocoa-rich chocolate compared to placebo on the lipid profile and anthropometric variables based on data from three clinical trials conducted in Colombia.

Methods

Meta-analysis of individual data from three randomized clinical trials conducted in Colombia. The entire population of

SUBMITTER: Alvarez L 

PROVIDER: S-EPMC7739050 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature