Effect of Intravitreous Aflibercept vs Vitrectomy With Panretinal Photocoagulation on Visual Acuity in Patients With Vitreous Hemorrhage From Proliferative Diabetic Retinopathy: A Randomized Clinical Trial.

ABSTRACT:

Importance

Vitreous hemorrhage from proliferative diabetic retinopathy can cause loss of vision. The best management approach is unknown.

Objective

To compare initial treatment with intravitreous aflibercept vs vitrectomy with panretinal photocoagulation for vitreous hemorrhage from proliferative diabetic retinopathy.

Design, setting, and participants

Randomized clinical trial at 39 DRCR Retina Network sites in the US and Canada including 205 adults with vison loss due to vitreous hemorrhage from proliferative diabetic retinopathy who were enrolled from November 2016 to December 2017. The final follow-up visit was completed in January 2020.

Interventions

Random assignment of eyes (1 per participant) to aflibercept (100 participants) or vitrectomy with panretina

SUBMITTER: Antoszyk AN 

PROVIDER: S-EPMC7739132 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature