Environmental Cadmium and Mortality from Influenza and Pneumonia in U.S. Adults.

ABSTRACT:

Background

Environmental cadmium exposure is widespread. In humans, cadmium is poorly excreted, triggers pulmonary inflammation, reduces pulmonary function, and enhances lung injury by respiratory syncytial virus.

Objectives

We examined the association of cadmium burden with mortality related to influenza or pneumonia.

Methods

This prospective analysis of the National Health and Nutrition Examination Survey (NHANES) included 7,173 and 8,678 participants ≥45 years of age enrolled in NHANES-III and NHANES 1999-2006, respectively. Associations were evaluated between cadmium and mortality from influenza or pneumonia during a median follow-up of 17.3 y (NHANES-III, based on creatinine-corrected urine cadmium) and 11.4 y (NHANES 1999-2006, based on blood cadmium). Survey-we

SUBMITTER: Park SK 

PROVIDER: S-EPMC7739956 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature