Mortality by mode of delivery among infants with spina bifida in Texas.

ABSTRACT:

Background

It is hypothesized that cesarean delivery may reduce mortality among infants with spina bifida (e.g., by reducing trauma to the open lesion); however, few studies have assessed this relationship.

Methods

We used the Texas Birth Defects Registry to identify neonates with spina bifida born between 1999 and 2014. The mode of delivery (main exposure) was abstracted from each subject's birth certificate. The vital status (main outcome) was determined based on the presence or absence of a death certificate. When a death certificate was present, survival time was calculated by subtracting the date of birth from the date of death. We then conducted multivariable Cox proportional hazards regression to estimate the adjusted hazard ratio between cesarean delivery and death p

SUBMITTER: Benjamin RH 

PROVIDER: S-EPMC7741424 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature