Clinical outcomes and inflammatory marker levels in patients with Covid-19 and obesity at an inner-city safety net hospital.

ABSTRACT:

Objectives

Patients with Covid-19 and obesity have worse clinical outcomes which may be driven by increased inflammation. This study aimed to characterize the association between clinical outcomes in patients with obesity and inflammatory markers.

Methods

We analyzed data for patients aged ≥18 years admitted with a positive SARS-CoV-2 PCR test. We used multivariate logistic regression to determine the association between BMI and intensive care unit (ICU) transfer and all-cause mortality. Inflammatory markers (C-reactive protein [CRP], lactate dehydrogenase [LDH], ferritin, and D-dimer) were compared between patients with and without obesity (body mass index [BMI] ≥30 kg/m2).

Results

Of 791 patients with Covid-19, 361 (45.6%) had obesity. In multivariate analyses, BMI

SUBMITTER: Mostaghim A 

PROVIDER: S-EPMC7744045 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature