Bridging Anxiety and Depression: A Network Approach in Anxious Adolescents.

ABSTRACT:

Background

The phenomenology and neurobiology of depressive symptoms in anxious youth is poorly understood.

Methods

Association networks of anxiety and depressive symptoms were developed in adolescents with generalized anxiety disorder (GAD; N=52, mean age: 15.4±1.6 years) who had not yet developed major depressive disorder. Community analyses were used to create consensus clusters of depressive and anxiety symptoms and to identify "bridge" symptoms between the clusters. In a subset of this sample (n=39), correlations between cortical thickness and depressive symptom severity was examined.

Results

Ten symptoms clustered into an anxious community, 5 clustered into a depressive community and 5 bridged the two communities: impaired schoolwork, excessive weeping, low self

SUBMITTER: Dobson ET 

PROVIDER: S-EPMC7744436 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature