Approaches to Optimize Medication Data Analysis in Clinical Cohort Studies.

ABSTRACT:

Objectives

Methods for pharmacoepidemiologic studies of large-scale data repositories are established. Although clinical cohorts of older adults often contain critical information to advance our understanding of medication risk and benefit, the methods best suited to manage medication data in these samples are sometimes unclear and their degree of validation unknown. We sought to provide researchers, in the context of a clinical cohort study of delirium in older adults, with guidance on the methodological tools to use data from clinical cohorts to better understand medication risk factors and outcomes.

Design

Prospective cohort study.

Setting

The Successful Aging After Elective Surgery (SAGES) prospective cohort.

Participants

A total of 560 older adults (aged ≥

SUBMITTER: Duprey MS 

PROVIDER: S-EPMC7744438 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature