Dried urine and salivary profiling for complete assessment of cortisol and cortisol metabolites.

ABSTRACT:

Aims/objectives

The primary aim of this study was to determine the utility of dried urine sampling in obtaining measures of cortisol and cortisol metabolites. Additional aims were to evaluate if a 4-spot dried urine collection is representative of a 24-hour urine collection and if expected diurnal cortisol patterns can be observed in samples from both urine and saliva.

Methods

Data from individuals with cortisol measures available from both a 4-spot dried urine collection and a 24-hour urine collection (n = 28) were evaluated. Of these 28, 20 also had concurrent liquid and dried 24-hour urine measures. Consistency between these methods was evaluated using paired t-tests and intraclass correlation coefficients (ICCs). In addition, data from individuals with concurrent measure

SUBMITTER: Newman M 

PROVIDER: S-EPMC7744704 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature