fshr: a fish sex-determining locus shows variable incomplete penetrance across flathead grey mullet populations.

ABSTRACT: Whole-genome sequencing data were produced from a single flathead grey mullet female and assembled into a draft genome sequence, whereas publicly available sequence data were used to obtain a male draft sequence. Two pools, each consisting of 60 unrelated individuals, respectively, of male and female fish were analyzed using Pool-Sequencing. Mapping and analysis of Pool-Seq data against the draft genome(s) revealed >30 loci potentially associated with sex, the most promising locus of which, encoding the follicle-stimulating hormone receptor (fshr) and harboring two missense variants, was genotyped on 245 fish from four Mediterranean populations. Genotype data showed that fshr represents a previously unknown sex-determining locus, although the incomplete association pat

SUBMITTER: Ferraresso S 

PROVIDER: S-EPMC7744951 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature