Feasibility and possible value of quantitative semi-automated diffusion weighted imaging volumetry of neuroblastic tumors.

ABSTRACT:

Background

To assess the feasibility and possible value of semi-automated diffusion weighted imaging (DWI) volumetry of whole neuroblastic tumors with apparent diffusion coefficient (ADC) map evaluation after neoadjuvant chemotherapy.

Methods

Pediatric patients who underwent surgical resection of neuroblastic tumors at our institution from 2013 to 2019 and who received a preoperative MRI scan with DWI after chemotherapy were included. Tumor volume was assessed with a semi-automated approach in DWI using a dedicated software prototype. Quantitative ADC values were calculated automatically of the total tumor volume after manual exclusion of necrosis. Manual segmentation in T1 weighted and T2 weighted sequences was used as reference standard for tumor volume comparison. The Stu

SUBMITTER: Gassenmaier S 

PROVIDER: S-EPMC7745476 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature