Glycemic excursion minimization in the management of type 2 diabetes: a novel intervention tested in a randomized clinical trial.

ABSTRACT:

Introduction

This study of adults with type 2 diabetes employed a non-inferiority hypothesis to investigate whether an innovative lifestyle focused on minimizing postnutrient blood glucose (BG) excursions (glycemic excursion minimization (GEM)) would be equivalent or superior to conventional weight loss (WL) therapy in regard to reducing HbA1c, and superior to WL when investigating physical, behavioral and psychological secondary outcomes. The impact of BG feedback on GEM efficacy was also investigated.

Research design and methods

178 adults with type 2 diabetes for ≤10 years, HbA1c ≥6.8%, and not using insulin were randomized to WL (n=40) or one of three versions of GEM. Didactic (GEM-D, n=39) taught participants to choose low-glycemic load foods, reduce sedentary time and

SUBMITTER: Cox DJ 

PROVIDER: S-EPMC7745682 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature