Ultra-high field (10.5 T) resting state fMRI in the macaque.

ABSTRACT: Resting state functional connectivity refers to the temporal correlations between spontaneous hemodynamic signals obtained using functional magnetic resonance imaging. This technique has demonstrated that the structure and dynamics of identifiable networks are altered in psychiatric and neurological disease states. Thus, resting state network organizations can be used as a diagnostic, or prognostic recovery indicator. However, much about the physiological basis of this technique is unknown. Thus, providing a translational bridge to an optimal animal model, the macaque, in which invasive circuit manipulations are possible, is of utmost importance. Current approaches to resting state measurements in macaques face unique challenges associated with signal-to-noise, the need for contrast agents

SUBMITTER: Yacoub E 

PROVIDER: S-EPMC7745777 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature