Effects of Inhaled Epoprostenol and Prone Positioning in Intubated Coronavirus Disease 2019 Patients With Refractory Hypoxemia.

ABSTRACT:

Objectives

To evaluate the effects of inhaled epoprostenol and prone positioning, individually and in combination in mechanically ventilated patients with coronavirus disease 2019 and refractory hypoxemia.

Design

Retrospective study.

Setting

Academic hospital adult ICUs.

Patients

Adult patients who received inhaled epoprostenol and prone positioning during invasive ventilation were enrolled. Patients were excluded if inhaled epoprostenol was initiated: 1) at an outside hospital, 2) after prone positioning was terminated, 3) during extracorporeal membrane oxygenation or cardiopulmonary resuscitation, and 4) with Pao₂/Fio₂ greater than 150 mm Hg.

Interventions

Inhaled epoprostenol and prone positioning.

Results

Of the 43 eligib

SUBMITTER: Li J 

PROVIDER: S-EPMC7746203 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature