Effect of family history, occupation and diet on the risk of Parkinson disease: A case-control study.

ABSTRACT:

Background

The aetiology of Parkinson's disease (PD) is still very controversial, with a peculiar lack of established risk factors or protective behavior.

Methods

We carried out a case-control study of 634 idiopathic PD patients admitted from 2011 to 2015 to two hospitals located in central Italy and 532 controls matched by hospital, gender and age (± 5 years). The study questionnaire included questions on host factors, family history, residence, occupation and lifestyle. Odds ratios (ORs) for PD and 95% confidence intervals (CIs) were estimated with logistic regression, adjusting for actual and potential confounders.

Results

A lower OR was observed in females (0.74; 95%CI:0.58-0.96), while older age classes showed a constantly increased risk for PD (p<0.005) starting

SUBMITTER: Torti M 

PROVIDER: S-EPMC7746265 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature