The predictive validity for mortality of the driving pressure and the mechanical power of ventilation.

ABSTRACT:

Background

Outcome prediction in critically ill patients under invasive ventilation remains extremely challenging. The driving pressure (ΔP) and the mechanical power of ventilation (MP) are associated with patient-centered outcomes like mortality and duration of ventilation. The objective of this study was to assess the predictive validity for mortality of the ΔP and the MP at 24 h after start of invasive ventilation.

Methods

This is a post hoc analysis of an observational study in intensive care unit patients, restricted to critically ill patients receiving invasive ventilation for at least 24 h. The two exposures of interest were the modified ΔP and the MP at 24 h after start of invasive ventilation. The primary outcome was 90-day mortality; secondary outcomes were ICU and

SUBMITTER: van Meenen DMP 

PROVIDER: S-EPMC7746416 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature