Ontology highlight
ABSTRACT:
SUBMITTER: Mesman AW
PROVIDER: S-EPMC7746708 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Mesman Annelies W AW Calderon Roger I RI Pollock Nira R NR Soto Martín M Mendoza Milagros M Coit Julia J Zhang Zibiao Z Aliaga Juan J Lecca Leonid L Holmberg Rebecca C RC Franke Molly F MF
Scientific reports 20201217 1
Tuberculosis (TB) diagnosis relies on a sputum sample, which cannot be easily obtained from all symptomatic patients. Mycobacterium tuberculosis DNA can be detected from oral swabs, a noninvasive, safe alternative sample type; however, reported sensitivities have been variable and likely depend on sample collection, processing procedures and host characteristics. We analyzed three buccal swab samples from 123 adults with culture-confirmed TB in Lima, Peru. We compared the sensitivity and specifi ...[more]