Serum amyloid A is a positive acute phase protein in Russian sturgeon challenged with Aeromonas hydrophila.

ABSTRACT: The immune system of sturgeons, one of the most ancient and economically valuable fish worldwide, is poorly understood. The lack of molecular tools and data about infection biomarkers hinders the possibility to monitor sturgeon health during farming and detect infection outbreaks. To tackle this issue, we mined publicly available transcriptomic datasets and identified putative positive acute-phase proteins (APPs) of Russian sturgeons that could be induced by a bacterial infection and monitored using non-invasive methods. Teleost literature compelled us to focus on five promising candidates: hepcidin, a warm acclimation associated hemopexin, intelectin, serum amyloid A protein (SAA) and serotransferrin. Among them, SAA was the most upregulated protein at the mRNA level in the liver of sturg

SUBMITTER: Castellano M 

PROVIDER: S-EPMC7746741 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature