Assessing Interocular Symmetry of the Foveal Cone Mosaic.

ABSTRACT:

Purpose

To test the hypothesis that foveal cone topography is symmetrical between contralateral eyes.

Methods

We used adaptive optics scanning light ophthalmoscopy to acquire images of the foveal cone mosaic in each eye of 58 subjects with normal vision (35 female, 23 male). Cones were semiautomatically identified over a 300 × 300-µm foveal area. From these cone coordinates, maps of cone density were derived, and we extracted estimates of peak cone density from each map. Mosaic regularity was assessed using Voronoi cell area regularity (VCAR). Average roundness and average area of the 70%, 75%, 80%, 85%, and 90% of peak density isodensity contours were evaluated.

Results

The average peak cone density for right eyes was 180,286 cones/mm2 (n = 49) and for left eyes was

SUBMITTER: Cava JA 

PROVIDER: S-EPMC7746960 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature