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Irradiation induced inversions suppress recombination between the M locus and morphological markers in Aedes aegypti.


ABSTRACT:

Background

Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector population control methods, such as the sterile insect technique, are receiving renewed interest. However, availability of a reliable genetic sexing strategy is crucial, since there is almost zero tolerance for accidentally released females. Development of genetic sexing strains through classical genetics is hindered by genetic recombination that is not suppressed in males as is the case in many Diptera. Isolation of naturally-occurring or irradiation-induced inversions can enhance the genetic stability of genetic sexing strains developed through genetically linking desir

SUBMITTER: Augustinos AA 

PROVIDER: S-EPMC7747368 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature