The long non coding RNA H19 as a biomarker for breast cancer diagnosis in Lebanese women.

ABSTRACT: Breast cancer is the most common cancer in women worldwide. Minimally invasive percutaneous image-guided biopsies are the current cornerstone in the diagnosis of breast lesions detected on mammography/ultrasonography/MRI or palpable clinically. However, apparently benign breast disease seen on benign biopsies is a limiting factor for diagnosis and a risk factor of breast cancer especially in the high-risk category patients. Hypothesizing that molecular changes often occur before morphological variations, the levels of the LncRNA H19 were measured in anonymous tissues obtained from 79 women's image guided breast biopsies, and correlated with cancer progression and aggressiveness. Using a double-blinded approach, H19 might be attributed an interesting role of a more sensitive biomarker in co

SUBMITTER: Elias-Rizk T 

PROVIDER: S-EPMC7747713 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature