Human Papillomavirus Same Genotype Persistence and Risk: A Systematic Review.

ABSTRACT:

Objective

The aim of the study was to examine whether high-grade cervical intraepithelial neoplasia (CIN) was more closely associated with human papillomavirus (HPV) same-genotype persistence (SGTP) versus clearance of prior infection with a subsequent infection by a new genotype (genotype switch [GS]), clearance of HPV infection, or acquisition of a new HPV infection after a negative infection status, during a follow-up testing subsequent to abnormal screening results.

Materials and methods

MEDLINE, Cochrane Library, Health Technology Assessment, and clinicaltrials.gov were searched from January 2000 to July 2019 for prospective controlled trials and observational studies of women and retrospective studies using HPV assays with extended- or full-genotype reporting. The prim

SUBMITTER: Bonde J 

PROVIDER: S-EPMC7748037 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature