Predicting and Managing Treatment Non-Response in Posttraumatic Stress Disorder.

ABSTRACT:

Purpose of review

This review aims to synthesize existing research regarding the definition of treatment resistance in posttraumatic stress disorder (PTSD), predictors of treatment non-response to first-line interventions, and emerging second-line PTSD treatment options into an accessible resource for the practicing clinician.

Recent findings

The concept of treatment resistance in PTSD is currently poorly defined and operationalized. There are no well-established predictors of treatment non-response utilized in routine clinical care, but existing research identifies several potential candidate markers, including male gender, low social support, chronic and early life trauma exposure, comorbid psychiatric disorders, severe PTSD symptoms, and poor physical health. The most pro

SUBMITTER: Fonzo GA 

PROVIDER: S-EPMC7748158 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature