Ventricular synchrony is not significantly determined by absolute myocardial perfusion in patients with chronic heart failure: A ¹³N-ammonia PET study.

ABSTRACT:

Background

It is thought that heart failure (HF) patients may benefit from the evaluation of mechanical (dys)synchrony, and an independent inverse relationship between myocardial perfusion and ventricular synchrony has been suggested. We explore the relationship between quantitative myocardial perfusion and synchrony parameters when accounting for the presence and extent of fixed perfusion defects in patients with chronic HF.

Methods

We studied 98 patients with chronic HF who underwent rest and stress Nitrogen-13 ammonia PET. Multivariate analyses of covariance were performed to determine relevant predictors of synchrony (measured as bandwidth, standard deviation, and entropy).

Results

In our population, there were 43 (44%) women and 55 men with a mean age of 71 ± 9.6

SUBMITTER: Juarez-Orozco LE 

PROVIDER: S-EPMC7749096 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature