Biomarker-Concordant Steroid Use in Critically Ill Patients with Pneumonia.

ABSTRACT:

Objectives

To evaluate the frequency and consequences of prescribing corticosteroids for pneumonia in a biomarker-concordant manner.

Patients and methods

This was a single-center retrospective cohort study of adults with pneumonia admitted to the medical intensive care unit (ICU) at Mayo Clinic in Rochester, Minnesota, between January 1, 2009, and June 30, 2014. Steroid use was "biomarker concordant" if given when C-reactive protein (CRP) was ≥150 mg/L or withheld when CRP was <150 mg/L, and vice versa for biomarker discordant.

Results

Of 3481 ICU admissions with community-acquired pneumonia, 169 (4.9%) had CRPs measured within 48 hours of admission to the ICU. Steroid use in the ICU was biomarker concordant in 88 (52%) patients and biomarker discordant in 81 (48%) pa

SUBMITTER: Odeyemi YE 

PROVIDER: S-EPMC7749267 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature