Association between GPx-1 polymorphisms and personality traits in healthy Chinese-Han subjects.

ABSTRACT:

Objectives

Cloninger developed the three-dimensional personality theory and Tridimensional Personality Questionnaire (TPQ), which shows that some dimensions of personality traits are heritable and related to neurotransmitters including dopamine. glutathione peroxidase 1 (GPx1) plays an important role in metabolic dopamine change and closely relates to neurological and psychiatric disorders. The impact of GPx-1 polymorphisms has been rarely explored in the field of personality traits. We decide to explore the relationships between them in healthy Chinese-Han subjects by using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).

Methods

In our study, 493 healthy Chinese-Han participants (male = 234, female = 259) were recruited. 2 ml of EDTA-treat

SUBMITTER: Shao X 

PROVIDER: S-EPMC7749609 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature