Neural activation during anticipation of monetary gain or loss does not associate with positive subjective response to alcohol in binge drinkers.

ABSTRACT:

Background

Alcohol use disorder (AUD) remains an unresolved source of morbidity and mortality. Psychopharmacological challenge studies and neuroimaging experiments are two methods used to identify risk of problematic substance use. The present study combined these two approaches by examining associations between self-reported stimulation, sedation, liking or wanting more after a dose of alcohol and neural-based responses to anticipation of monetary gain and loss.

Methods

Young adult binge drinkers (N = 56) aged 21-29, with no history of Substance Use Disorder completed five experimental sessions. These included four laboratory sessions in which they rated their subjective responses to alcohol (0.8 g/kg for men, 0.68 g/kg for women) or placebo, and a single functional magneti

SUBMITTER: Pabon E 

PROVIDER: S-EPMC7750248 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature