The cingulum in very preterm infants relates to language and social-emotional impairment at 2 years of term-equivalent age.

ABSTRACT:

Background

Relative to full-term infants, very preterm infants exhibit disrupted white matter (WM) maturation and problems related to development, including motor, cognitive, social-emotional, and receptive and expressive language processing.

Objective

The present study aimed to determine whether regional abnormalities in the WM microstructure of very preterm infants, as defined relative to those of full-term infants at a near-term age, are associated with neurodevelopmental outcomes at the age of 18-22 months.

Methods

We prospectively enrolled 89 very preterm infants (birth weight < 1500 g) and 43 normal full-term control infants born between 2016 and 2018. All infants underwent a structural brain magnetic resonance imaging scan at near-term age. The diffusion tensor

SUBMITTER: Lee HJ 

PROVIDER: S-EPMC7750449 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature