Successive epidemic waves of cholera in South Sudan between 2014 and 2017: a descriptive epidemiological study.

ABSTRACT:

Background

Between 2014 and 2017, successive cholera epidemics occurred in South Sudan within the context of civil war, population displacement, flooding, and drought. We aim to describe the spatiotemporal and molecular features of the three distinct epidemic waves and explore the role of vaccination campaigns, precipitation, and population movement in shaping cholera spread in this complex setting.

Methods

In this descriptive epidemiological study, we analysed cholera linelist data to describe the spatiotemporal progression of the epidemics. We placed whole-genome sequence data from pandemic Vibrio cholerae collected throughout these epidemics into the global phylogenetic context. Using whole-genome sequence data in combination with other molecular attributes, we characteri

SUBMITTER: Jones FK 

PROVIDER: S-EPMC7750463 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature