Risk of Ischemic Stroke in Patients With Atrial Fibrillation After Extracranial Hemorrhage.

ABSTRACT:

Background and purpose

Anticoagulation therapy not only reduces the risk of ischemic stroke in atrial fibrillation (AF) but also predisposes patients to hemorrhagic complications. There is limited knowledge on the risk of first-ever ischemic stroke in patients with AF after extracranial hemorrhage (ECH).

Methods

We conducted a retrospective study using the California State Inpatient Database including all nonfederal hospital admissions in California from 2005 to 2011. The exposure variable was hospitalization with a diagnosis of ECH with a previous diagnosis of AF. The outcome variable was a subsequent hospitalization with acute ischemic stroke. We excluded patients with stroke before or at the time of ECH diagnosis. We calculated adjusted hazard ratios for ischemic stroke d

SUBMITTER: Zhou E 

PROVIDER: S-EPMC7751804 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature