Low medication adherence is associated with decline in health-related quality of life: results of a longitudinal analysis among older women and men with hypertension.

ABSTRACT:

Objective

The aim of this study was to determine the association of low antihypertensive medication adherence with decline in health-related quality of life (HRQOL) over 1 year.

Methods

We used data from older men and women with hypertension (n = 1525) enrolled in the Cohort Study of Medication Adherence among Older Adults. Adherence was measured using the validated self-report four-item Krousel-Wood Medication Adherence Scale (K-Wood-MAS-4) (low adherence = score ≥1) and prescription refill-based proportion of days covered (PDC) (low adherence = PDC < 0.80). We defined decline in HRQOL as a decrease in Mental Component Summary (MCS) or Physical Component Summary (PCS) score (from the RAND 36-Item Health Survey 1.0 administered at two time points - at the time of adherence a

SUBMITTER: Peacock E 

PROVIDER: S-EPMC7752228 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature